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本剧基于Leonie Frieda的书籍《Catherine de Medici: Renaissance Queen of France》创作，《革命之路》编剧Justin Haythe负责剧本，Stacie Passon担任首播集在内的多集导演。
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爱家男子雷·库珀发誓要让制药公司付出代价，因为在他的妻子（阿德里娅·阿霍纳饰）死于癌症之前，该公司将一种或能救命的药物从市场上撤下。然而，这场真相探寻之旅却让他和女儿瑞秋（伊莎贝拉·梅塞德饰）陷入险境，自此雷的任务变成了复仇，以保护自己唯一的家人。
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A romantic adventure with an intriguing blend of modern and classic touches, THE RENDEZVOUS throws together RACHEL, a Jewish-American doctor and JAKE, an Arab-American government bureaucrat, who are trying to solve the mysterious death of Rachel's treasure hunting brother. Racing around the world, they find themselves being hunted by a doomsday group calling themselves the Armageddonites who believe Rachel and Jake possess an ancient script discovered by Rachel's brother that could bring about the end of days.
Caught in the middle of a plot to hasten the end of mankind, Rachel and Jake need to solve a murder, save the world and discover for themselves that treasure is where you find it.